A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Clinical management of voice and breathing problems in two patients with vagus nerve stimulation therapy
Tekijät: Alantie Sonja, Makkonen Tanja, Hietala Satu, Peltola Jukka
Kustantaja: John Libbey Eurotext
Julkaisuvuosi: 2021
Journal: Epileptic Disorders
Tietokannassa oleva lehden nimi: EPILEPTIC DISORDERS
Lehden akronyymi: EPILEPTIC DISORD
Vuosikerta: 23
Numero: 1
Aloitussivu: 173
Lopetussivu: 179
Sivujen määrä: 7
ISSN: 1294-9361
eISSN: Epileptic Disorders
Tiivistelmä
We report two cases highlighting the diversity of vagal nerve stimulation (VNS)-related effects on voice and breathing in patients with refractory epilepsy. The patients had both implantation and stimulation-related side effects, which lasted for several months, impacting on their quality of life. The adverse effects appear to be due to recurrent laryngeal nerve paralysis-related vocal cord hypofunction and stimulation-related vocal fold spasms, however, their inter-relationship is complex. In one of the patients, we were able to utilize the novel programming capabilities of the VNS device to reduce the laryngeal side effects without compromising therapeutic efficacy.
We report two cases highlighting the diversity of vagal nerve stimulation (VNS)-related effects on voice and breathing in patients with refractory epilepsy. The patients had both implantation and stimulation-related side effects, which lasted for several months, impacting on their quality of life. The adverse effects appear to be due to recurrent laryngeal nerve paralysis-related vocal cord hypofunction and stimulation-related vocal fold spasms, however, their inter-relationship is complex. In one of the patients, we were able to utilize the novel programming capabilities of the VNS device to reduce the laryngeal side effects without compromising therapeutic efficacy.
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