A1 Journal article – refereed
Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support
List of Authors: Suchsland Ruth, Appel Bettina, Virta Pasi, Müller Sabine
Publisher: ROYAL SOC CHEMISTRY
Publication year: 2021
Journal: RSC Advances
Journal name in source: RSC ADVANCES
Journal acronym: RSC ADV
Volume number: 11
Issue number: 7
Number of pages: 5
eISSN: 2046-2069
DOI: http://dx.doi.org/10.1039/d0ra10941j
URL: https://pubs.rsc.org/en/content/articlelanding/2021/RA/D0RA10941J#!divAbstract
Abstract
In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained much attention. We here describe the preparation of such trinucleotide synthons on a soluble support using a disulphide linker.
In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained much attention. We here describe the preparation of such trinucleotide synthons on a soluble support using a disulphide linker.
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