A1 Refereed original research article in a scientific journal

Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support



Authors: Suchsland Ruth, Appel Bettina, Virta Pasi, Müller Sabine

Publisher: ROYAL SOC CHEMISTRY

Publication year: 2021

Journal: RSC Advances

Journal name in source: RSC ADVANCES

Journal acronym: RSC ADV

Volume: 11

Issue: 7

First page : 3892

Last page: 3896

Number of pages: 5

eISSN: 2046-2069

DOI: https://doi.org/10.1039/d0ra10941j

Web address : https://pubs.rsc.org/en/content/articlelanding/2021/RA/D0RA10941J#!divAbstract

Self-archived copy’s web address: https://research.utu.fi/converis/portal/detail/Publication/53410037


Abstract
In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained much attention. We here describe the preparation of such trinucleotide synthons on a soluble support using a disulphide linker.

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Last updated on 2024-26-11 at 19:41