A1 Journal article – refereed

Synthesis of fully protected trinucleotide building blocks on a disulphide-linked soluble support




List of Authors: Suchsland Ruth, Appel Bettina, Virta Pasi, Müller Sabine

Publisher: ROYAL SOC CHEMISTRY

Publication year: 2021

Journal: RSC Advances

Journal name in source: RSC ADVANCES

Journal acronym: RSC ADV

Volume number: 11

Issue number: 7

Number of pages: 5

eISSN: 2046-2069

DOI: http://dx.doi.org/10.1039/d0ra10941j

URL: https://pubs.rsc.org/en/content/articlelanding/2021/RA/D0RA10941J#!divAbstract


Abstract
In recent years, preparation of fully protected trinucleotide phosphoramidites as synthons for the codon-based synthesis of gene libraries as well as for the assembly of oligonucleotides from blockmers has gained much attention. We here describe the preparation of such trinucleotide synthons on a soluble support using a disulphide linker.

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Last updated on 2021-24-06 at 09:26