B1 Journal article

Maternal psychological distress during gestation is associated with infant food allergy




List of Authors: Lukkarinen Minna, Puosi Emma, Kataja Eeva-Leena, Korhonen Laura S, Lukkarinen Heikki, Karlsson Linnea, Karlsson Hasse

Publisher: WILEY

Publication year: 2021

Journal: Pediatric Allergy and Immunology

Journal name in source: PEDIATRIC ALLERGY AND IMMUNOLOGY

Journal acronym: PEDIAT ALLERG IMM-UK

Volume number: 32

Issue number: 4

Number of pages: 6

ISSN: 0905-6157

eISSN: 1399-3038

DOI: http://dx.doi.org/10.1111/pai.13449

URL: https://onlinelibrary.wiley.com/doi/10.1111/pai.13449


Abstract
Maternal psychological distress (depressive and anxiety) symptoms during gestation are shown to relate to elevated risk of offspring atopic diseases. According to the Developmental Origins of Health and Disease theory, this association could result from the programming effect of maternal psychological distress predisposing the offspring to aberrant stress and immune responses. The timing and duration of the distress exposure seem to be relevant but the chronicity aspect has not been studied earlier in humans. We aimed to investigate how the chronicity and severity of maternal distress symptoms during gestation associate with the outcome of infant food allergy at the age of 6 months in nearly 2000 mother-infant dyads from a prospective FinnBrain Birth Cohort.


Last updated on 2021-24-06 at 08:54