B1 Non-refereed article in a scientific journal
A rare case of oral epithelioid sarcoma of the gingiva
Authors: Hagström Jaana, Mesimäki Karri, Apajalahti Satu, Haglund Caj, Rönty Mikko, Sarlomo-Rikala Maarit
Publisher: MOSBY-ELSEVIER
Publication year: 2011
Journal: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology
Journal name in source: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY
Journal acronym: ORAL SURG ORAL MED O
Volume: 111
Issue: 4
First page : E25
Last page: E28
Number of pages: 4
ISSN: 1079-2104
DOI: https://doi.org/10.1016/j.tripleo.2010.12.014
Abstract
Epithelioid sarcoma (ES) is a rare malignant soft tissue tumor. ES can be classified into proximal, distal, and fibroma-like subtypes. These tumors show both mesenchymal and epithelial immunophenotypes. Microscopically, the proximal type ES is usually characterized by nodules of spindle and epithelioid cells growing in granuloma-like pattern often presenting with central necrosis. Immunohistochemically these tumors are vimentin, pancytokeratin, and usually EMA (80%) positive. CD34 (50%) and CD99 (25%) may be positive, and occasionally SMA and S-100 immunopositivity has been reported. No specific genetic alterations have been found in ES. As far as we know, this is the first case in the literature to present ES in gingival mucosa. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111:e25-e28)
Epithelioid sarcoma (ES) is a rare malignant soft tissue tumor. ES can be classified into proximal, distal, and fibroma-like subtypes. These tumors show both mesenchymal and epithelial immunophenotypes. Microscopically, the proximal type ES is usually characterized by nodules of spindle and epithelioid cells growing in granuloma-like pattern often presenting with central necrosis. Immunohistochemically these tumors are vimentin, pancytokeratin, and usually EMA (80%) positive. CD34 (50%) and CD99 (25%) may be positive, and occasionally SMA and S-100 immunopositivity has been reported. No specific genetic alterations have been found in ES. As far as we know, this is the first case in the literature to present ES in gingival mucosa. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;111:e25-e28)
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