A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Biodegradable behavior and mechanical performance of Mg-Zn alloys in acidic urinary environments relevant to renal tubular acidosis
Tekijät: Li, Yi; Lu, Chao; Shen, Kai; Wu, Xia; Bai, Jingyuan; Liu, Zhihui; Cai, Zhihui; Liu, Weiqing; Xiong, Chunmei; Papageorgiou, Anastassios; Zhao, Zhanyong; Morozova, Natalia Borisovna; Staiger, Mark; Tie, Di
Kustantaja: Elsevier BV
Julkaisuvuosi: 2026
Lehti: Progress in Natural Science: Materials International
Vuosikerta: 36
Numero: 2
Aloitussivu: 382
Lopetussivu: 392
ISSN: 1002-0071
eISSN: 1745-5391
DOI: https://doi.org/10.1016/j.pnsc.2026.01.001
Julkaisun avoimuus kirjaamishetkellä: Ei avoimesti saatavilla
Julkaisukanavan avoimuus : Osittain avoin julkaisukanava
Verkko-osoite: https://doi.org/10.1016/j.pnsc.2026.01.001
Magnesium-zinc (Mg-Zn) alloys have attracted considerable attention as implant materials due to their inherent biodegradability. Herein, we evaluate their performance in the acidic urinary environment characteristic of renal tubular acidosis (RTA). To this end, the corrosion response, degradation performance, and mechanical properties of Mg-xZn alloys with different zinc contents were examined in artificial urine (pH 5.7) designed to mimic RTA conditions. Relative to pure Mg, the Mg-6Zn alloy demonstrated a 2.35 times higher hardness and a 2.58 times higher ultimate tensile strength (UTS), reflecting substantial mechanical reinforcement. Initial immersion tests indicated that corrosion severity first decreased and then increased with higher Zn content. After 30 days, although the overall degradation of Mg-Zn alloys was greater than that of pure Mg, a reduced susceptibility to pitting corrosion was observed. Furthermore, the alloys maintained a UTS above 148.9 MPa and an elongation of 3.17 %, confirming preservation of essential mechanical integrity during degradation. These results highlight the potential of Mg-Zn alloys as functional biodegradable materials and provide insights for the design of next-generation magnesium-based bioresorbable implants.
Julkaisussa olevat rahoitustiedot:
This work was supported by National Natural Science Foundation of China (52171235, 5241102867 and 52111540263), Guangdong Science and Technology Program (2025ZDZX2028), Xinjiang Science and Technology Program (2025E01044), Yangjiang Talent Revitalization Program (RCZX2023004), and Guangdong Ocean University (YJR24003).
