A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
HERITABLE DENTIN DEFECTS - NOSOLOGY, PATHOLOGY, AND TREATMENT
Tekijät: RANTA H, LUKINMAA PL, WALTIMO J
Kustantaja: WILEY-LISS
Julkaisuvuosi: 1993
Journal: American journal of medical genetics
Tietokannassa oleva lehden nimi: AMERICAN JOURNAL OF MEDICAL GENETICS
Lehden akronyymi: AM J MED GENET
Vuosikerta: 45
Numero: 2
Aloitussivu: 193
Lopetussivu: 200
Sivujen määrä: 8
ISSN: 0148-7299
DOI: https://doi.org/10.1002/ajmg.1320450209
Tiivistelmä
Heritable dentin defects have been divided into 2 main categories: dentinogenesis imperfecta (DI) and dentin dysplasia (DD). Recent studies have shown that they share many features in common. Of the connective tissue diseases, only osteogenesis imperfecta (OI) has been linked to these disorders. So far, no definitive relation between the type of OI and the dental involvement can be established. Familial occurrence of DI with OI cannot be comprehensively explained by mutations in type I collagen genes. No information about the gene defects in DD is available. At the ultrastructural level, the organization of the normally cross-striated collagen fibers in the dentin matrix varies markedly in patients affected by DI.
Heritable dentin defects have been divided into 2 main categories: dentinogenesis imperfecta (DI) and dentin dysplasia (DD). Recent studies have shown that they share many features in common. Of the connective tissue diseases, only osteogenesis imperfecta (OI) has been linked to these disorders. So far, no definitive relation between the type of OI and the dental involvement can be established. Familial occurrence of DI with OI cannot be comprehensively explained by mutations in type I collagen genes. No information about the gene defects in DD is available. At the ultrastructural level, the organization of the normally cross-striated collagen fibers in the dentin matrix varies markedly in patients affected by DI.
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