Expanding the Paradigm of Structure-Based Drug Design: Molecular Dynamics Simulations Support the Development of New Pyridine-Based Protein Kinase C-Targeted Agonists

: Lautala, Saara; Provenzani, Riccardo; Tarvainen, Ilari; Sirna, Katia; Karhu, S. Tuuli; Grazhdankin, Evgeni; Lehtinen, Antti K.; Sa'd, Hanan; Koivuniemi, Artturi; Xhaard, Henri; Tuominen, Raimo K.; Talman, Virpi; Bunker, Alex; Yli-Kauhaluoma, Jari

: 2023

 Journal of Medicinal Chemistry

: 66

: 7

: 4588

: 4602

: 0022-2623

: 1520-4804

DOI: https://doi.org/10.1021/acs.jmedchem.2c01448