A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Perioperative hyperglycaemia in elective arthroplasties. Should we do better?
Tekijät: Marianne Ylikoski, Janne J. Jokinen, Jorma Lahtela, Markku J. Kauppi, Heini Huhtala, Heidi Immonen, Raine Tiihonen
Kustantaja: WILEY
Julkaisuvuosi: 2020
Journal: Acta Anaesthesiologica Scandinavica
Tietokannassa oleva lehden nimi: ACTA ANAESTHESIOLOGICA SCANDINAVICA
Lehden akronyymi: ACTA ANAESTH SCAND
Vuosikerta: 64
Numero: 9
Aloitussivu: 1253
Lopetussivu: 1261
Sivujen määrä: 9
ISSN: 0001-5172
DOI: https://doi.org/10.1111/aas.13666
Tiivistelmä
Background Perioperative dysglycaemia is associated with deleterious outcomes but guidelines to improve glucose management are poorly or inconsistently adhered to. We evaluated glucose management among diabetic and non-diabetic patients undergoing elective hip or knee arthroplasty. Methods Capillary plasma glucose (CPG) was measured prospectively four times daily of 209 patients undergoing elective hip or knee surgery. Actions of the attending teams to CPG values and detection of patients at risk were analysed. Results A total of 209 patients were enrolled. All diabetic patients on insulin (6/6) had hyperglycaemia (>= 7.8 mmol/l) more than twice and severe hyperglycaemia (>10 mmol/l) at least once. Of the 27 diabetic patients not on insulin 26 (96.3%) had CPG >= 7.8 mmol/l >= 2 times and 17 (63%) >10 mmol/l. The corresponding figures of the 176 non-diabetic patients were 137 (77.8%) and 61 (34.7%). Severe hyperglycaemia occurred in 54/176 (30.1%) of the non-diabetic patients with pre-operative HbA1c 10 mmol/l, none was treated. Patients with a FINDRISC score >= 12 (corresponding to moderate to high risk of diabetes) and hyperglycaemia went unnoticed. Conclusions Hyperglycaemia is common among elective orthopaedic surgery patients with or without diabetes. More than 80% of the 209 patients had hyperglycaemia and 40% had severe hyperglycaemia. None of the patients was treated according to guidelines and none of the patients at risk of hyperglycaemia or diabetes was noticed. There is an obvious need for further education and support by diabetes specialists. Clinical trial registration Clinical trials, gov. NCT03306810.
Background Perioperative dysglycaemia is associated with deleterious outcomes but guidelines to improve glucose management are poorly or inconsistently adhered to. We evaluated glucose management among diabetic and non-diabetic patients undergoing elective hip or knee arthroplasty. Methods Capillary plasma glucose (CPG) was measured prospectively four times daily of 209 patients undergoing elective hip or knee surgery. Actions of the attending teams to CPG values and detection of patients at risk were analysed. Results A total of 209 patients were enrolled. All diabetic patients on insulin (6/6) had hyperglycaemia (>= 7.8 mmol/l) more than twice and severe hyperglycaemia (>10 mmol/l) at least once. Of the 27 diabetic patients not on insulin 26 (96.3%) had CPG >= 7.8 mmol/l >= 2 times and 17 (63%) >10 mmol/l. The corresponding figures of the 176 non-diabetic patients were 137 (77.8%) and 61 (34.7%). Severe hyperglycaemia occurred in 54/176 (30.1%) of the non-diabetic patients with pre-operative HbA1c 10 mmol/l, none was treated. Patients with a FINDRISC score >= 12 (corresponding to moderate to high risk of diabetes) and hyperglycaemia went unnoticed. Conclusions Hyperglycaemia is common among elective orthopaedic surgery patients with or without diabetes. More than 80% of the 209 patients had hyperglycaemia and 40% had severe hyperglycaemia. None of the patients was treated according to guidelines and none of the patients at risk of hyperglycaemia or diabetes was noticed. There is an obvious need for further education and support by diabetes specialists. Clinical trial registration Clinical trials, gov. NCT03306810.
Turun yliopiston Tutkimustietojärjestelmän portaali