A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä
Synthetic gametes and the non-identity problem: the babies of tomorrow
Tekijät: Villalba, Adrian; Räsänen, Joona
Kustantaja: Cell Press
Julkaisuvuosi: 2025
Journal: Trends in Genetics
ISSN: 0168-9525
eISSN: 1362-4555
DOI: https://doi.org/10.1016/j.tig.2025.08.004
Verkko-osoite: https://doi.org/10.1016/j.tig.2025.08.004
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/499862526
Synthetic DNA technologies may eventually enable the creation of synthetic gametes, which would offer precise control over genetic inheritance. This possibility raises profound ethical questions about human identity, genetic selection, and evolutionary boundaries. While synthetic gametes sidestep person-affecting ethical concerns, they present challenges for balancing reproductive autonomy and minimizing heritable disease, prompting interdisciplinary reflection.
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This work is funded by Fundació Víctor Grífols i Lucas (BEC-2024-07) and the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie Actions grant agreement No. 101081293.