A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Humoral Immunity to Measles, Mumps, Rubella, Diphtheria, Tetanus and Pertussis After Cancer Treatment in Children



Tekijät: Sundell, Susanna; Laine, Miia; Järvelä, Liisa; Peltola, Ville; Vuorinen, Tytti; Lähteenmäki, Päivi; Schuez-Havupalo, Linnea

Kustantaja: Wiley

Kustannuspaikka: HOBOKEN

Julkaisuvuosi: 2025

Journal: Cancer reports

Tietokannassa oleva lehden nimi: Cancer Reports

Lehden akronyymi: CANCER REP-US

Artikkelin numero: e70155

Vuosikerta: 8

Numero: 5

Sivujen määrä: 7

ISSN: 2573-8348

eISSN: 2573-8348

DOI: https://doi.org/10.1002/cnr2.70155

Verkko-osoite: https://doi.org/10.1002/cnr2.70155

Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/498504843


Tiivistelmä
Background

Treatment for pediatric malignancies has distinct effects on the immune system.

Aims

Our aim was to measure humoral immunity to measles, mumps and rubella (MMR), and diphtheria, tetanus and acellular pertussis (DTaP) vaccines after pediatric cancer treatment.

Method

We assessed IgG titers of 52 children against the vaccine antigens post-treatment.

Results

After completed primary vaccination series for MMR and DTaP before treatment, post-treatment there was a considerable proportion of patients with below-reference titers against pertussis, diphtheria and tetanus, but only few subjects showed below-reference titers against measles, mumps and rubella. Our findings may have implications when considering re-vaccination policies.


Ladattava julkaisu

This is an electronic reprint of the original article.
This reprint may differ from the original in pagination and typographic detail. Please cite the original version.

Julkaisussa olevat rahoitustiedot: 
This work was supported by the Turku University Hospital Foundation.


Last updated on 2025-19-06 at 13:52