A1 Refereed original research article in a scientific journal

Cardiac resynchronization therapy - Part 2 - Issues during and after device




AuthorsBax JJ, Abraham T, Barold SS, Breithardt OA, Fung JWH, Garrigue S, Gorcsan J, Hayes DL, Kass DA, Knuuti J, Leclercq C, Linde C, Mark DB, Monaghan MJ, Nihoyannopoulos P, Schalij MJ, Stellbrink C, Yu CM

PublisherELSEVIER SCIENCE INC

Publication year2005

JournalJournal of the American College of Cardiology

Journal name in sourceJOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Journal acronymJ AM COLL CARDIOL

Volume46

Issue12

First page 2168

Last page2182

Number of pages15

ISSN0735-1097

DOIhttps://doi.org/10.1016/j.jacc.2005.09.020


Abstract
Encouraged by the clinical success of cardiac resynchronization therapy (CRT), the implantation rate has increased exponentially, although several limitations and unresolved issues of CRT have been identified. This review concerns issues that are encountered during implantation of CRT devices, including the role of electroanatomical mapping, whether CRT implantation should be accompanied by simultaneous atrioventricular nodal ablation in patients with atrial fibrillation, procedural complications, and when to consider surgical left ventricular lead positioning. Furthermore, (echocardiographic) CRT optimization and assessment of CRT benefits after implantation are highlighted. Also, controversial issues such as the potential value of CRT in patients with mild heart failure or narrow QRS complex are addressed. Finally, open questions concerning when to combine CRT with implantable cardioverter-defibritlator therapy and the cost-effectiveness of CRT are discussed.



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