A1 Refereed original research article in a scientific journal
Asymptomatic Right Atrial Thrombosis After Acute Lymphoblastic Leukemia Treatment
Authors: Kirsten B Jarvis, Nadine G Andersson, Mia Giertz, Liisa Järvelä, Olle Lindinger, Satu Långström, Riitta Niinimäki, Sauli Palmu, Sonata S Trakymiene, Ruta Tuckuviene, Kaisa Vepsäläinen, Susanna Ranta, Tony Frisk
Publisher: Wolters Kluver
Publication year: 2021
Journal: Journal of Pediatric Hematology/Oncology
DOI: https://doi.org/10.1097/MPH.0000000000001848
Right atrial thrombosis is a rare, but potentially serious complication
of acute lymphoblastic leukemia treatment. We conducted a retrospective
multicenter study to assess the incidence, treatment, and outcome of
asymptomatic right atrial thrombosis detected at routine
echocardiography of children after acute lymphoblastic leukemia
treatment in the Nordic and Baltic countries. Eleven (2.7%, 95%
confidence interval, 1.4-4.9) of 406 patients had asymptomatic right
atrial thrombosis, ranging from 10 to 25 mm at detection. Three patients
were treated with anticoagulation. None of the thromboses affected
cardiac function, and they showed neither sign of progress nor
spontaneous or treatment-related regress at follow-up.
