Increased number of parvovirus B19 infections in southeast Scotland in 2012-2013.
Tekijät: Al Shukri I, Hamilton F, Evans M, Cooper S, McKenzie G, Willocks L, Templeton K, Harvala H
Julkaisuvuosi: 2015
Journal: Clinical Microbiology and Infection
Tietokannassa oleva lehden nimi: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Lehden akronyymi: Clin Microbiol Infect
Vuosikerta: 21
Numero: 2
Aloitussivu: 193
Lopetussivu: 6
ISSN: 1198-743X
eISSN: 1469-0691
DOI: https://doi.org/10.1016/j.cmi.2014.09.009
Tiivistelmä
Parvovirus B19 (B19V) infections are a common but under-investigated and under-reported cause of intrauterine infections. An increased number of acute B19V infections was identified in the Edinburgh area in 2012-2013, with 123 infections diagnosed in 33 pregnant women, 76 non-pregnant women and 14 men. All except one pregnant woman were asymptomatic. An overall infection rate of 18% was measured in pregnant women who were tested following B19V exposure (26/141). Furthermore, a 7% seroconversion rate was recorded in non-immune pregnant women who were re-tested after exposure (7/104). A high fetal loss rate (25%; 3/12) was observed in those who had acute B19V infection in early pregnancy (<11 weeks) whereas all pregnancies progressed to term in those where acute infection occurred after a gestational age of 12 weeks. These results suggest that more efforts should be targeted to investigate suspected B19V infections in early pregnancy during epidemic seasons.
Parvovirus B19 (B19V) infections are a common but under-investigated and under-reported cause of intrauterine infections. An increased number of acute B19V infections was identified in the Edinburgh area in 2012-2013, with 123 infections diagnosed in 33 pregnant women, 76 non-pregnant women and 14 men. All except one pregnant woman were asymptomatic. An overall infection rate of 18% was measured in pregnant women who were tested following B19V exposure (26/141). Furthermore, a 7% seroconversion rate was recorded in non-immune pregnant women who were re-tested after exposure (7/104). A high fetal loss rate (25%; 3/12) was observed in those who had acute B19V infection in early pregnancy (<11 weeks) whereas all pregnancies progressed to term in those where acute infection occurred after a gestational age of 12 weeks. These results suggest that more efforts should be targeted to investigate suspected B19V infections in early pregnancy during epidemic seasons.
Turun yliopiston Tutkimustietojärjestelmän portaali