Convalescent plasma for COVID-19: male gender, older age and hospitalisation associated with high neutralising antibody levels, England, 22 April to 12 May 2020.
Authors: Mehew J, Johnson R, Roberts D, Harvala H
Publication year: 2020
Journal: Eurosurveillance
Journal name in source: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Journal acronym: Euro Surveill
Volume: 25
Issue: 45
ISSN: 1025-496X
eISSN: 1560-7917
DOI: https://doi.org/10.2807/1560-7917.ES.2020.25.45.2001754
Abstract
We analysed factors associated with neutralising antibody levels in 330 convalescent plasma donors. Women and younger donors were more likely not to have measurable neutralising antibodies, while higher antibody levels were observed in men, in older donors and in those who had been hospitalised. These data will be of value in the timely recruitment of convalescent plasma donors most likely to have high levels of neutralising antibodies for ongoing studies investigating its effectiveness.
We analysed factors associated with neutralising antibody levels in 330 convalescent plasma donors. Women and younger donors were more likely not to have measurable neutralising antibodies, while higher antibody levels were observed in men, in older donors and in those who had been hospitalised. These data will be of value in the timely recruitment of convalescent plasma donors most likely to have high levels of neutralising antibodies for ongoing studies investigating its effectiveness.
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