A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Organomercury oligonucleotide-polydopamine nanoparticle assemblies discriminate between target sequences by Hg(ii)-mediated base pairing
Tekijät: Kotammagari, Tharun K.; Al-Waeel, Majid; Lukkari, Jukka; Lönnberg, Tuomas
Kustantaja: Royal Society of Chemistry
Julkaisuvuosi: 2024
Journal: RSC Advances
Tietokannassa oleva lehden nimi: RSC ADVANCES
Vuosikerta: 14
Numero: 51
Aloitussivu: 38279
Lopetussivu: 38284
eISSN: 2046-2069
DOI: https://doi.org/10.1039/d4ra07922a
Verkko-osoite: https://doi.org/10.1039/D4RA07922A
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/477189139
A fluorescently tagged oligonucleotide hybridization probe incorporating a single 5-mercuricytosine residue was synthesized and found to adsorb on polydopamine nanoparticles much more strongly than its unmetallated counterpart. Hybridization with target sequences led to release of the probe from the nanoparticle to varying degrees depending on the nucleobase opposite to 5-mercuricytosine.
Ladattava julkaisu This is an electronic reprint of the original article. |  |
