A3 Refereed book chapter or chapter in a compilation book
Shaping Microbiota During the First 1000 Days of Life
Authors: Marta Selma-Royo, Maria Tarrazó, Izaskun García-Mantrana, Carlos Gómez-Gallego, Seppo Salminen, Maria Carmen Collado
Editors: Stefano Guandalini, Flavia Indrio
Publisher: Springer New York LLC
Publication year: 2019
Book title : Probiotics and Child Gastrointestinal Health
Journal name in source: Advances in Experimental Medicine and Biology
Series title: Advances in Experimental Medicine and Biology
Volume: 1125
First page : 3
Last page: 24
Number of pages: 22
ISBN: 978-3-030-14635-1
eISBN: 978-3-030-14636-8
ISSN: 0065-2598
DOI: https://doi.org/10.1007/5584_2018_312
The data obtained in prior studies suggest that early microbial exposition begins prior to conception and gestation. Given that the host-microbe interaction is shaped by the immune system response, it is important to understand the key immune system-microbiota relationship during the period from conception to the first years of life. The present work summarizes the available evidence concerning early microbiota exposure within the male and the female reproductive tracts at the point of conception and during gestation, focusing on the potential impact on infant development during the first 1000 days of life. Furthermore, we conclude that some dietary strategies including specific probiotics could become potentially valuable tools to modulate the gut microbiota during this early critical window of opportunity for targeted health outcomes throughout the entire lifespan.