Association of endocrine disrupting chemicals with male reproductive health




Helena E. Virtanen, Katharina M. Main, Jorma Toppari

Ilpo Huhtaniemi, Luciano Martini

2nd edition

PublisherElsevier

2019

Encyclopedia of Endocrine Diseases (Second Edition)

1

802

811

978-0-12-812199-3

978-0-12-812200-6



Research on endocrine disrupting chemicals continues the long tradition
of reproductive and endocrine toxicology. The most harmful chemicals for
male reproduction are antiandrogenic compounds that interfere with both
development and function of the testis. This leads to birth defects
such as cryptorchidism and hypospadias, structural anomalies of the
testis that may cause testicular cancer and poor semen quality. Human
epidemiological studies rarely detect any association between single
chemical exposures and adverse effect. We are currently missing
comprehensive analyses of the adverse effects of life-long combined
exposures to multiple chemicals, which would reflect our real life
environment.



Last updated on 2024-26-11 at 13:14