A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Health-Related Quality of Life in 5-Year-Old Very Low Birth Weight Infants
Tekijät: Rautava L, Hakkinen U, Korvenranta E, Andersson S, Gissler M, Hallman M, Korvenranta H, Leipala J, Linna M, Peltola M, Tammela O, Lehtonen L
Kustantaja: MOSBY-ELSEVIER
Julkaisuvuosi: 2009
Journal: Journal of Pediatrics
Tietokannassa oleva lehden nimi: JOURNAL OF PEDIATRICS
Lehden akronyymi: J PEDIATR-US
Vuosikerta: 155
Numero: 3
Aloitussivu: 338
Lopetussivu: 343
Sivujen määrä: 6
ISSN: 0022-3476
DOI: https://doi.org/10.1016/j.jpeds.2009.03.061
Tiivistelmä
Objective To investigate the effect of preterm birth, the time of birth, and birth hospital level and district on health-related quality of life (HRQoL) and quality-adjusted life years (QALYs).Study design This national study included all very low birth weight infants (VLBWIs; birth weight <= 1500 g or gestational age < 32 weeks) born in Finland between 2000 and 2003 (n = 1169; live-born, n = 900) and full-term controls (n = 368). Register data and parental questionnaires were used. The relationships among HRQoL and QALYs at age 5 years and preterm birth, time of birth, and the level and district of the birth hospital were studied.Results HRQoL at age 5 years was lower and 1.3 QALYs were lost in VLBWIs compared with controls. Regional differences in the QALYs of VLBWIs were found among the 5 university hospital districts. Birth hospital level or birth outside office hours had no effect on the QALYs of live-born VLBWIs. The adjusted HRQoL total score was not affected by birth outside office hours or by the birth hospital level or district.Conclusions Differences in QALYs related to hospital district suggest variation in the care of VLBWIs that needs to be addressed. (J Pediatr 2009; 155:338-43).
Objective To investigate the effect of preterm birth, the time of birth, and birth hospital level and district on health-related quality of life (HRQoL) and quality-adjusted life years (QALYs).Study design This national study included all very low birth weight infants (VLBWIs; birth weight <= 1500 g or gestational age < 32 weeks) born in Finland between 2000 and 2003 (n = 1169; live-born, n = 900) and full-term controls (n = 368). Register data and parental questionnaires were used. The relationships among HRQoL and QALYs at age 5 years and preterm birth, time of birth, and the level and district of the birth hospital were studied.Results HRQoL at age 5 years was lower and 1.3 QALYs were lost in VLBWIs compared with controls. Regional differences in the QALYs of VLBWIs were found among the 5 university hospital districts. Birth hospital level or birth outside office hours had no effect on the QALYs of live-born VLBWIs. The adjusted HRQoL total score was not affected by birth outside office hours or by the birth hospital level or district.Conclusions Differences in QALYs related to hospital district suggest variation in the care of VLBWIs that needs to be addressed. (J Pediatr 2009; 155:338-43).
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