Respiratory symptoms, bronchial hyper-responsiveness, and eosinophilic airway inflammation in patients with moderate-to-severe atopic dermatitis

: Kyllonen H, Malmberg P, Remitz A, Rytila P, Metso T, Helenius I, Haahtela T, Reitamo S

Publisher: BLACKWELL PUBLISHING

: 2006

Clinical and Experimental Allergy

CLINICAL AND EXPERIMENTAL ALLERGY

: CLIN EXP ALLERGY

: 36

: 2

: 192

: 197

: 6

: 0954-7894

DOI: https://doi.org/10.1111/j.1365-2222.2006.02419.x

BHR and eosinophilic airway inflammation are more common in patients with AD than in control subjects. The highest prevalences were seen in patients with AD who were SPT positive and had high IgE levels. Longitudinal studies are needed to assess the outcome of patients with signs of airway disease, in order to identify those who need early initiation of asthma treatment.