A1 Refereed original research article in a scientific journal
The European Eye Epidemiology spectral-domain optical coherence tomography classification of macular diseases for epidemiological studies
Authors: Gattoussi S, Buitendijk GHS, Peto T, Leung I, Schmitz-Valckenberg S, Oishi A, Wolf S, Deak G, Delcourt C, Klaver CCW, Korobelnik JF, Acar N, Anas-Tosopoulos E, Azuara-Blanco A, Berendschot T, Bertelsen G, Binquet C, Bird A, Bobak M, Larsen MB, Boon C, Bourne R, Bretillon L, Broe R, Bron A, Buitendijk G, Cachulo ML, Capuano V, Carriere I, Chakravarthy U, Chan M, Chang P, Colijn J, Cree A, Creuzot-Garcher C, Cumberland P, Cunha-Vaz J, Daien V, De Jong E, Deak G, Delcourt C, Delyfer MN, den Hollan-Der A, Dietzel M, Erke MG, Faria P, Farinha C, Fauser S, Finger R, Fletcher A, Foster P, Found P, Gorgels T, Grauslund J, Grus F, Hammond C, Helmer C, Hense HW, Hermann M, Hoehn R, Hogg R, Holz F, Hoyng C, Jansonius N, Janssen S, Kersten E, Khawaja A, Klaver C, Korobelnik JF, Lamparter J, Le Goff M, Lechanteur Y, Lehtimaki T, Lotery A, Mauschitz M, Meester M, Merle B, zu Westrup VM, Midena E, Miotto S, Mirshahi A, Mohan-Said S, Muldrew A, Murta J, Nickels S, Nunes S, Pfeiffer N, Piermarocchi S, Prokofyeva E, Rahi J, Raitakari O, Rauscher F, Ribeiro L, Rougier MB, Rudnicka A, Sahel J, Salonikiou A, Sanchez C, Schuster A, Schweitzer C, Segato T, Shehata J, Silva R, Silvestri G, Souied E, Speckauskas M, Springelkamp H, Tapp R, Topouzis F, van Leeuwen E, Verhoeven V, Verzijden T, Von Hanno T, Wiedemann P, Williams K, Wolfram C, Yip J, Zerbib J, Zerbib J, Yip J, Wolfram C, Williams K, Wiedemann P, Von Hanno T
Publisher: WILEY
Publication year: 2019
Journal: Acta Ophthalmologica
Journal name in source: ACTA OPHTHALMOLOGICA
Journal acronym: ACTA OPHTHALMOL
Volume: 97
Issue: 4
First page : 364
Last page: 371
Number of pages: 8
ISSN: 1755-375X
eISSN: 1755-3768
DOI: https://doi.org/10.1111/aos.13883
Purpose The aim of the European Eye Epidemiology (E3) consortium was to develop a spectral-domain optical coherence tomography (SD-OCT)-based classification for macular diseases to standardize epidemiological studies. Methods A European panel of vitreoretinal disease experts and epidemiologists belonging to the E3 consortium was assembled to define a classification for SD-OCT imaging of the macula. A series of meeting was organized, to develop, test and finalize the classification. First, grading methods used by the different research groups were presented and discussed, and a first version of classification was proposed. This first version was then tested on a set of 50 SD-OCT images in the Bordeaux and Rotterdam centres. Agreements were analysed and discussed with the panel of experts and a final version of the classification was produced. Results Definitions and classifications are proposed for the structure assessment of the vitreomacular interface (visibility of vitreous interface, vitreomacular adhesion, vitreomacular traction, epiretinal membrane, full-thickness macular hole, lamellar macular hole, macular pseudo-hole) and of the retina (retinoschisis, drusen, pigment epithelium detachment, hyper-reflective clumps, retinal pigment epithelium atrophy, intraretinal cystoid spaces, intraretinal tubular changes, subretinal fluid, subretinal material). Classifications according to size and location are defined. Illustrations of each item are provided, as well as the grading form. Conclusion The E3 SD-OCT classification has been developed to harmonize epidemiological studies. This homogenization will allow comparing and sharing data collection between European and international studies.
