Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo



: Marttila-Ichihara F, Smith DJ, Stolen C, Yegutkin GG, Elima K, Mercier N, Kiviranta R, Pihlavisto M, Alaranta S, Pentikainen U, Pentikainen O, Fulop F, Jalkanen S, Salmi M

Publisher: WILEY-LISS

: Hoboken, New Jersey

: 2006

: Arthritis and Rheumatism

: ARTHRITIS AND RHEUMATISM

: ARTHRITIS RHEUM

: 54

: 9

: 2852

: 2862

: 11

: 0004-3591

DOI: https://doi.org/10.1002/art.22061


Conclusion. These are the first data to demonstrate that the enzymatic activity of the atypical endothelial adhesion molecule AOC3, and possibly that of other closely related ecto-oxidases, is crucial for leukocyte exit from the vessels in inflamed joints in vivo.



Last updated on 2024-26-11 at 17:47