Effect of controlled hypoglycaemia on sympathetic skin response in patients with Type 1 diabetes and control subjects - UTU Research Portal

A1 Refereed original research article in a scientific journal

Effect of controlled hypoglycaemia on sympathetic skin response in patients with Type 1 diabetes and control subjects

Authors: Koivikko ML, Airaksinen KEJ, Perkiomaki JS, Huikuri HV, Tapanainen JS, Kallio MA

Publisher: WILEY-BLACKWELL

Publication year: 2015

Journal: Diabetic Medicine

Journal name in source: DIABETIC MEDICINE

Journal acronym: DIABETIC MED

Volume: 32

Issue: 4

First page : 556

Last page: 560

Number of pages: 5

ISSN: 0742-3071

DOI: https://doi.org/10.1111/dme.12619

Abstract

ConclusionsDuring hypoglycaemia the number of repetitive synchronous sympathetic skin responses was related to increased sweating according to the hypoglycaemic symptom score. This is best explained by central nervous system reactions. The sympathetic skin responses of the patients with Type 1 diabetes had a weaker correlation with hypoglycaemia and its symptoms, which was possibly attributable to an adaptation or a dysfunction of the patients' sudomotor pathways.