A1 Refereed original research article in a scientific journal
Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci
Authors: Al Olama AA, Benlloch S, Antoniou AC, Giles GG, Severi G, Neal DE, Hamdy FC, Donovan JL, Muir K, Schleutker J, Henderson BE, Haiman CA, Schumacher FR, Pashayan N, Pharoah PDP, Ostrander EA, Stanford JL, Batra J, Clements JA, Chambers SK, Weischer M, Nordestgaard BG, Ingles SA, Sorensen KD, Orntoft TF, Park JY, Cybulski C, Maier C, Doerk T, Dickinson JL, Cannon-Albright L, Brenner H, Rebbeck TR, Zeigler-Johnson C, Habuchi T, Thibodeau SN, Cooney KA, Chappuis PO, Hutter P, Kaneva RP, Foulkes WD, Zeegers MP, Lu YJ, Zhang HW, Stephenson R, Cox A, Southey MC, Spurdle AB, FitzGerald L, Leongamornlert D, Saunders E, Tymrakiewicz M, Guy M, Dadaev T, Little SJ, Govindasami K, Sawyer E, Wilkinson R, Herkommer K, Hopper JL, Lophatonanon A, Rinckleb AE, Kote-Jarai Z, Eeles RA, Easton DF
Publisher: AMER ASSOC CANCER RESEARCH
Publication year: 2015
Journal: Cancer Epidemiology, Biomarkers and Prevention
Journal name in source: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
Journal acronym: CANCER EPIDEM BIOMAR
Volume: 24
Issue: 7
First page : 1121
Last page: 1129
Number of pages: 9
ISSN: 1055-9965
eISSN: 1538-7755
DOI: https://doi.org/10.1158/1055-9965.EPI-14-0317
Impact: We demonstrate that the risk profiling based on SNPs can identify men at substantially increased or reduced risk that could have useful implications for targeted prevention and screening programs. (C) 2015 AACR.