A1 Refereed original research article in a scientific journal
Laryngeal cancer in Finland: A 5-year follow-up study of 366 patients
Authors: Aaro Haapaniemi, Petri Koivunen, Kauko Saarilahti, Ilpo Kinnunen, Jussi Laranne, Leena-Maija Aaltonen, Mervi Närkiö, Paula Lindholm, Reidar Grénman, Antti Mäkitie, Timo Atula; The Finnish Head and Neck Oncology Working Group
Publication year: 2016
Journal: Head and Neck
Volume: 38
Issue: 1
First page : 36
Last page: 43
Number of pages: 8
ISSN: 1043-3074
DOI: https://doi.org/10.1002/hed.23834
ABSTRACT: Background. The purpose of this study was to acquire
nationwide data on the management and outcome of laryngeal squamous
cell carcinoma (SCC) in Finnish university hospitals over a 5-year
posttreatment follow-up.
Methods. All records of patients diagnosed and treated for primary laryngeal
SCC during 2001 to 2005 were reviewed.
Results. Three hundred sixty-six patients with laryngeal cancer were
identified, 360 of whom had laryngeal SCC. Three hundred forty-two
patients with laryngeal SCC (95%) were treated with curative intent.
Five-year disease-specific survival (DSS) for T1a, T1b, T2, T3, and T4
glottic SCC was 100%, 95%, 78%, 79%, and 53%, respectively. The
corresponding figures for T1 to T4 supraglottic SCC were 68%, 54%,
72%, and 59%.
Conclusion. Results of this nationwide study give a general overview of
the outcome of unselected patients treated with unified guidelines.
Patients with T2 tumors, usually treated with radiotherapy (RT), had a
worse prognosis than expected. This patient group warrants further
investigation and possibly treatment intensification. VC 2015 Wiley Periodicals,
Inc. Head Neck 00: 000–000, 2015
