Studies on association of mRNA cap-analogues with a synthetic dodecapeptide Dgiepmwedekn



: Niedzwiecka-Kornas A, Przedmojski R, Balaspiri L, Wieczorek Z, Stepinski J, Jankowska M, Lonnberg H, Darzynkiewicz E, Stolarski R

Publisher: MARCEL DEKKER INC

: 1999

Nucleosides & nucleotides

NUCLEOSIDES & NUCLEOTIDES

: NUCLEOS NUCLEOT

: 18

: 4-5

: 1105

: 1106

: 2

: 0732-8311

DOI: https://doi.org/10.1080/15257779908041660


H-1 NMR and fluorescence were applied to a study of interactions between dinucleotide analogues of mRNA. cap and a peptide DGIEPMWEDEKN. Structures of the m(7)G-Trp complexes were determined by means of the ring current anisotropy theory, and their features were refered to the known X-ray structure of the eIF4E-m(7)GDP associate.



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