Reduced cross-protection against influenza A(H3N2) subgroup 3C.2a and 3C.3a viruses among Finnish healthcare workers vaccinated with 2013/14 seasonal influenza vaccine - UTU Tutkimustietojärjestelmä

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Reduced cross-protection against influenza A(H3N2) subgroup 3C.2a and 3C.3a viruses among Finnish healthcare workers vaccinated with 2013/14 seasonal influenza vaccine

Tekijät: Haveri A, Ikonen N, Julkunen I, Kantele A, Anttila VJ, Ruotsalainen E, Nohynek H, Lyytikalnen O, Savolainen-Kopra C

Kustantaja: EUR CENTRE DIS PREVENTION & CONTROL

Julkaisuvuosi: 2015

Journal: Eurosurveillance

Tietokannassa oleva lehden nimi: EUROSURVEILLANCE

Lehden akronyymi: EUROSURVEILLANCE

Vuosikerta: 20

Numero: 5

Aloitussivu: 13

Lopetussivu: 20

Sivujen määrä: 8

ISSN: 1560-7917

DOI: https://doi.org/10.2807/1560-7917.ES2015.20.5.21028

Tiivistelmä

Virus strains in the seasonal influenza vaccine for the 2014/15 northern hemisphere season remained unchanged from those in 2013/14. During spring 2014, drifted influenza A(H3N2) viruses, subgroup 3C.3a, were detected in Finland; another subgroup, 3C.2a, emerged in the 2014/15 season and has predominated. We monitored antibody responses against vaccine and epidemic strains (2013/14 and 2014/15) among Finnish healthcare workers after influenza vaccination with the 2013/14 vaccine. The data suggest reduced cross-protection towards both subgroups of drifted A(H3N2) viruses.