Radiation Dosimetry and Biodistribution of the Hypoxia Tracer F-18-EF5 in Oncologic Patients




Lin LL, Silvoniemi A, Stubbs JB, Rengan R, Suilamo S, Solin O, Divgi C, Eskola O, Sorger JM, Stabin MG, Kachur A, Hahn SM, Gronroos TJ, Forsback S, Evans SM, Koch CJ, Minn H

PublisherMARY ANN LIEBERT INC

2012

Cancer Biotherapy and Radiopharmaceuticals

CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

CANCER BIOTHER RADIO

7

27

7

412

419

8

1084-9785

DOIhttps://doi.org/10.1089/cbr.2011.1130



Conclusions: F-18-EF5 was demonstrated to be safe for patients, and the radiation exposure is clinically acceptable. As with any radiotracer with primary excretion in the urine, the bladder-wall dose can be minimized by active hydration and frequent voiding.




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