Radiation Dosimetry and Biodistribution of the Hypoxia Tracer F-18-EF5 in Oncologic Patients
: Lin LL, Silvoniemi A, Stubbs JB, Rengan R, Suilamo S, Solin O, Divgi C, Eskola O, Sorger JM, Stabin MG, Kachur A, Hahn SM, Gronroos TJ, Forsback S, Evans SM, Koch CJ, Minn H
Publisher: MARY ANN LIEBERT INC
: 2012
: Cancer Biotherapy and Radiopharmaceuticals
: CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
: CANCER BIOTHER RADIO
: 7
: 27
: 7
: 412
: 419
: 8
: 1084-9785
DOI: https://doi.org/10.1089/cbr.2011.1130
Conclusions: F-18-EF5 was demonstrated to be safe for patients, and the radiation exposure is clinically acceptable. As with any radiotracer with primary excretion in the urine, the bladder-wall dose can be minimized by active hydration and frequent voiding.