A1 Refereed original research article in a scientific journal
Intrapericardial, But Not Extrapericardial, Fat Is an Independent Predictor of Impaired Hyperemic Coronary Perfusion in Coronary Artery Disease
Authors: Bucci M, Joutsiniemi E, Saraste A, Kajander S, Ukkonen H, Saraste M, Pietila M, Sipila HT, Teras M, Maki M, Airaksinen KEJ, Hartiala J, Knuuti J, Iozzo P
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Publication year: 2011
Journal: Arteriosclerosis, Thrombosis, and Vascular Biology
Journal name in source: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Journal acronym: ARTERIOSCL THROM VAS
Number in series: 1
Volume: 31
Issue: 1
First page : 211
Last page: 218
Number of pages: 11
ISSN: 1079-5642
DOI: https://doi.org/10.1161/ATVBAHA.110.213827
Abstract
Conclusion-CAD is accompanied by augmented fat depots surrounding the heart, which are negatively related to coronary flow hyperemia. Among fat depots, IPF was the only independent predictor of hyperemic MBF, supporting the hypothesis of a direct paracrine/vasocrine effect. (Arterioscler Thromb Vasc Biol. 2011;31:211-218.)
Conclusion-CAD is accompanied by augmented fat depots surrounding the heart, which are negatively related to coronary flow hyperemia. Among fat depots, IPF was the only independent predictor of hyperemic MBF, supporting the hypothesis of a direct paracrine/vasocrine effect. (Arterioscler Thromb Vasc Biol. 2011;31:211-218.)