A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Cardiovascular risk factors in 2011 and secular trends since 2007: The Cardiovascular Risk in Young Finns Study.
Tekijät: Nuotio J, Oikonen M, Magnussen CG, Jokinen E, Laitinen T, Hutri-Kähönen N, Kähönen M, Lehtimäki T, Taittonen L, Tossavainen P, Jula A, Loo BM, Viikari JS, Raitakari OT, Juonala M
Julkaisuvuosi: 2014
Journal: Scandinavian Journal of Public Health
Tietokannassa oleva lehden nimi: Scandinavian journal of public health
Lehden akronyymi: Scand J Public Health
Vuosikerta: 42
Numero: 7
Aloitussivu: 563
Lopetussivu: 571
Sivujen määrä: 9
ISSN: 1651-1905
DOI: https://doi.org/10.1177/1403494814541597
AIMS\nCardiovascular risk factor levels in 2011 and 4-year changes between 2007 and 2011 were examined using data collected in follow-ups of the Cardiovascular Risk in Young Finns Study.\nMETHODS\nThe study population comprised 2063 Finnish adults aged 34-49 years (45% male). Lipid and blood pressure levels, glucose and anthropometry were measured and life style risk factors examined with questionnaires.\nRESULTS\nMean total cholesterol level in 2011 was 5.19 mmol/l, low density lipoprotein (LDL)-cholesterol 3.27 mmol/l, high density lipoprotein (HDL)-cholesterol 1.33 mmol/l, and triglycerides 1.34 mmol/l. Using American Diabetes Association criteria, Type 2 diabetes (T2D) was observed in 4.1% and prediabetes (fasting glucose 5.6-6.9 mmol/l or glycated hemoglobin 5.7-6.4%) diagnosed for 33.8% of the participants. Significant changes (P < 0.05) between 2007 and 2011 included an increase in waist circumference (3.3%) in women. In both sexes, systolic (-3.0% in women, -4.0% in men) and diastolic (-3.0% in women, -3.3% in men) blood pressure and triglycerides (-3.4% in women, -6.5% in men) decreased during follow-up. CONCLUSIONS PREVIOUSLY OBSERVED FAVORABLE TRENDS IN LDL-CHOLESTEROL LEVELS HAVE LEVELED OFF AMONG A SAMPLE OF YOUNG AND MIDDLE-AGED ADULTS IN FINLAND TRIGLYCERIDE AND BLOOD PRESSURE LEVELS HAVE DECREASED OVER ONE-THIRD OF THE STUDY POPULATION HAD PREDIABETES AND MAY BE AT INCREASED RISK FOR T2D: