Hsa-miR-31-3p Expression Is Linked to Progression-free Survival in Patients with KRAS Wild-type Metastatic Colorectal Cancer Treated with Anti-EGFR Therapy

: Manceau G, Imbeaud S, Thiebaut R, Liebaert F, Fontaine K, Rousseau F, Genin B, Le Corre D, Didelot A, Vincent M, Bachet JB, Chibaudel B, Bouche O, Landi B, Bibeau F, Leroy K, Penault-Llorca F, Van Laethem JL, Demetter P, Tejpar S, Rossi S, Mosakhani N, Osterlund P, Ristamaki R, Sarhadi V, Knuutila S, Boige V, Andre T, Laurent-Puig P

Publisher: AMER ASSOC CANCER RESEARCH

: 2014

: Clinical Cancer Research

: CLINICAL CANCER RESEARCH

: CLIN CANCER RES

: 20

: 12

: 3338

: 3347

: 10

: 1078-0432

DOI: https://doi.org/10.1158/1078-0432.CCR-13-2750

Conclusion: Hsa-miR-31-3p seems to be a new mCRC biomarker whose expression level allows for the identification of patients with wild-type KRAS mCRC who are more likely to respond to anti-EGFR therapy. Clin Cancer Res; 20(12); 3338-47.(C) 2014 AACR.