A2 Refereed review article in a scientific journal
Chapter Eight – Brown Adipose Tissue in Humans: Detection and Functional Analysis Using PET (Positron Emission Tomography), MRI (Magnetic Resonance Imaging), and DECT (Dual Energy Computed Tomography)
Authors: Magnus Borga, Kirsi A. Virtanen, Thobias Romu, Olof Dahlqvist Leinhard,
Anders Persson, Pirjo Nuutila, Sven Enerbäck
Publication year: 2014
Journal: Methods in Enzymology
Volume: 537
First page : 141
Last page: 159
Number of pages: 19
ISBN: 978-0-12-411619-1
ISSN: 0076-6879
DOI: https://doi.org/10.1016/B978-0-12-411619-1.00008-2
Abstract
If the beneficial effects of brown adipose tissue (BAT) on whole body metabolism, as observed in nonhuman experimental models, are to be translated to humans, tools that accurately measure how BAT influences human metabolism will be required. This chapter discusses such techniques, how they can be used, what they can measure and also some of their limitations. The focus is on detection and functional analysis of human BAT and how this can be facilitated by applying advanced imaging technology such as positron emission tomography, magnetic resonance imaging, and dual energy computed tomography.
If the beneficial effects of brown adipose tissue (BAT) on whole body metabolism, as observed in nonhuman experimental models, are to be translated to humans, tools that accurately measure how BAT influences human metabolism will be required. This chapter discusses such techniques, how they can be used, what they can measure and also some of their limitations. The focus is on detection and functional analysis of human BAT and how this can be facilitated by applying advanced imaging technology such as positron emission tomography, magnetic resonance imaging, and dual energy computed tomography.
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