Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice - UTU Research Portal

A1 Refereed original research article in a scientific journal

Peroxisomal membrane channel Pxmp2 in the mammary fat pad is essential for stromal lipid homeostasis and for development of mammary gland epithelium in mice

Authors: Vapola MH, Rokka A, Sormunen RT, Alhonen L, Schmitz W, Conzelmann E, Warri A, Grunau S, Antonenkov VD, Hiltunen JK

Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCE

Publication year: 2014

Journal: Developmental Biology

Journal name in source: DEVELOPMENTAL BIOLOGY

Journal acronym: DEV BIOL

Volume: 391

Issue: 1

First page : 66

Last page: 80

Number of pages: 15

ISSN: 0012-1606

eISSN: 1095-564X

DOI: https://doi.org/10.1016/j.ydbio.2014.03.022

Abstract

The results point to disturbances of lipid metabolism in the mammary fat pad that in turn may result in abnormal epithelial growth. The work reveals impaired mammary gland development as a new category of peroxisomal disorders. (C) 2014 Elsevier Inc. All rights reserved.