Zn2+ promoted hydrolysis of RNA

: Mikkola S, Zagorowska I, Lonnberg H

Publisher: MARCEL DEKKER INC

: 1999

: Nucleosides & nucleotides

: NUCLEOSIDES & NUCLEOTIDES

: NUCLEOS NUCLEOT

: 18

: 6-7

: 1267

: 1268

: 2

: 0732-8311

DOI: https://doi.org/10.1080/07328319908044688

The Zn2+ promoted hydrolysis of phosphodiester bonds of RNA has been studied by using a series of model compounds from dinucleoside monophosphates to oligo- and polynucleotides. The results will be discussed with respect to complex formation between the metal ion catalysts and substrates.

Chemical sciences