A1 Refereed original research article in a scientific journal

The effect of the secondary structure of RNA on the reactivity of its phosphodiester bonds: The cleavage of phosphodiester bonds within hairpin loops in the presence and absence of metal ion catalysts



Authors: Mikkola S, Zagorowska I, Lonnberg H

Publication year: 1999

Journal: Collection of Czechoslovak Chemical Communications

Journal name in source: CHEMISTRY OF NUCLEIC ACID COMPONENTS

Journal acronym: COLL SYMPOS SERIES

Volume: 2

First page : 6

Last page: 10

Number of pages: 5

ISBN: 80-86241-04-1


Abstract
The cleavage of phosphodiester bonds within hairpin loops was studied in buffer solutions, in the presence and absence of metal ion catalysts. The aim of the work is to study the effect of a secondary structure on the inherent reactivity of phosphodiester bonds, and on the ability of metal ion based catalysts to enhance the cleavage.


Research Areas



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