A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Occurrence and analysis of rare cfiA-bft doubly positive Bacteroides fragilis strains
Tekijät: Soki J, Eitel Z, Terhes G, Nagy E, Urban E, on behalf of the ESCMID Study Group on Anaerobic Infections (incl. Könönen E)
Kustantaja: ELSEVIER SCI LTD
Julkaisuvuosi: 2013
Journal: Anaerobe
Tietokannassa oleva lehden nimi: ANAEROBE
Lehden akronyymi: ANAEROBE
Vuosikerta: 23
Aloitussivu: 70
Lopetussivu: 73
Sivujen määrä: 4
ISSN: 1075-9964
DOI: https://doi.org/10.1016/j.anaerobe.2013.06.008
Tiivistelmä
We detected four cfiA-bft1 doubly positive Bacteroides fragilis strains out of 486 B. fragilis isolates analyzed for antibiotic susceptibilities and antibiotic resistance genes from a recent pan-European survey. The prevalence of the enterotoxin bft genes was roughly equal among cfiA-negative and -positive B. fragilis strains. We also demonstrated that the cfiA-bft doubly positive strains had the most common B. fragilis genomic pattern (I.1.). Thus we concluded that the bft-carrying CTn86 conjugative transposons are mobile accounting for this unexpected simultaneous occurrence of the cfiA and bft genes. (c) 2013 Elsevier Ltd. All rights reserved.
We detected four cfiA-bft1 doubly positive Bacteroides fragilis strains out of 486 B. fragilis isolates analyzed for antibiotic susceptibilities and antibiotic resistance genes from a recent pan-European survey. The prevalence of the enterotoxin bft genes was roughly equal among cfiA-negative and -positive B. fragilis strains. We also demonstrated that the cfiA-bft doubly positive strains had the most common B. fragilis genomic pattern (I.1.). Thus we concluded that the bft-carrying CTn86 conjugative transposons are mobile accounting for this unexpected simultaneous occurrence of the cfiA and bft genes. (c) 2013 Elsevier Ltd. All rights reserved.
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