A1 Refereed original research article in a scientific journal
Myocardial Perfusion by CT Versus Hybrid Imaging
Authors: George RT, Mehra VC, Saraste A, Knuuti J
Publisher: W B SAUNDERS CO-ELSEVIER INC
Publication year: 2012
Journal: Cardiology Clinics
Journal name in source: CARDIOLOGY CLINICS
Journal acronym: CARDIOL CLIN
Number in series: 1
Volume: 30
Issue: 1
First page : 135
Last page: 146
Number of pages: 13
ISSN: 0733-8651
DOI: https://doi.org/10.1016/j.ccl.2011.11.007
Abstract
Coronary computed tomography angiography (CTA) is a reliable diagnostic test for the anatomic diagnosis of obstructive coronary artery disease (CAD). Although coronary CTA shows high sensitivity and negative predictive value for detecting stenosis greater than or equal to 50% diameter, it is limited in its ability to diagnose myocardial ischemia. Advances in computed tomography (CT) technology alone and technology that hybridizes CT with single-photon emission CT and positron emission tomography allow for the combined anatomic and physiologic diagnosis of CAD. This article summarizes these combined technologies, emphasizing the merits and limitations of each technology and their clinical implications.
Coronary computed tomography angiography (CTA) is a reliable diagnostic test for the anatomic diagnosis of obstructive coronary artery disease (CAD). Although coronary CTA shows high sensitivity and negative predictive value for detecting stenosis greater than or equal to 50% diameter, it is limited in its ability to diagnose myocardial ischemia. Advances in computed tomography (CT) technology alone and technology that hybridizes CT with single-photon emission CT and positron emission tomography allow for the combined anatomic and physiologic diagnosis of CAD. This article summarizes these combined technologies, emphasizing the merits and limitations of each technology and their clinical implications.
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