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Bioimpedance-based respiratory gating method for oncologic positron emission tomography (PET) imaging with first clinical results




AuthorsKoivumaki T, Vauhkonen M, Teuho J, Teras M, Hakulinen MA

Publication year2013

JournalJournal of Physics: Conference Series

Book title x

Journal name in sourceXV INTERNATIONAL CONFERENCE ON ELECTRICAL BIO-IMPEDANCE (ICEBI) & XIV CONFERENCE ON ELECTRICAL IMPEDANCE TOMOGRAPHY (EIT)

Journal acronymJ PHYS CONF SER

Article numberUNSP 012037

Volume434

Number of pages4

ISSN1742-6588

DOIhttps://doi.org/10.1088/1742-6596/434/1/012037


Abstract
Respiratory motion may cause significant image artefacts in positron emission tomography/computed tomography (PET/CT) imaging. This study introduces a new bioimpedance-based gating method for minimizing respiratory artefacts. The method was studied in 12 oncologic patients by evaluating the following three parameters: maximum metabolic activity of radiopharmaceutical accumulations, the size of these targets as well as their target-to-background ratio. The bioimpedance-gated images were compared with non-gated images and images that were gated with a reference method, chest wall motion monitoring by infrared camera. The bioimpedance method showed clear improvement as increased metabolic activity and decreased target volume compared to non-gated images and produced consistent results with the reference method. Thus, the method may have great potential in the future of respiratory gating in nuclear medicine imaging.



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