A1 Refereed original research article in a scientific journal
Fragmentation of thymidine induced by ultraviolet photoionization and thermal degradation
Authors: Levola H, Kooser K, Rachlew E, Nommiste E, Kukk E
Publisher: ELSEVIER SCIENCE BV
Publication year: 2013
Journal: International Journal of Mass Spectrometry
Journal name in source: INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
Journal acronym: INT J MASS SPECTROM
Volume: 353
First page : 7
Last page: 11
Number of pages: 5
ISSN: 1387-3806
DOI: https://doi.org/10.1016/j.ijms.2013.08.008
Abstract
Fragmentation of gas phase thymidine at different temperatures was studied with vacuum ultraviolet radiation and time-of-flight spectroscopy. Partial ion yield measurements were carried out in order to study the appearance energies of thymidine and its main fragments. The appearance energies of thymidine and its deoxyribose- and thymine-based fragments were determined to be 8.39, 8.77 and 8.81 eV, independently of temperature. The thermal decomposition of the sample was observed to start around 138-139 degrees C and it was explained by the breakage of the glycosidic bond, accompanied by hydrogen transfer from the deoxyribose ring to the thymine base. (C) 2013 Elsevier B.V. All rights reserved.
Fragmentation of gas phase thymidine at different temperatures was studied with vacuum ultraviolet radiation and time-of-flight spectroscopy. Partial ion yield measurements were carried out in order to study the appearance energies of thymidine and its main fragments. The appearance energies of thymidine and its deoxyribose- and thymine-based fragments were determined to be 8.39, 8.77 and 8.81 eV, independently of temperature. The thermal decomposition of the sample was observed to start around 138-139 degrees C and it was explained by the breakage of the glycosidic bond, accompanied by hydrogen transfer from the deoxyribose ring to the thymine base. (C) 2013 Elsevier B.V. All rights reserved.
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