A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Discovery and application of insertion-deletion (INDEL) polymorphisms for QTL mapping of early life-history traits in Atlantic salmon
Tekijät: Vasemagi A, Gross R, Palm D, Paaver T, Primmer CR
Kustantaja: BIOMED CENTRAL LTD
Julkaisuvuosi: 2010
Journal: BMC Genomics
Tietokannassa oleva lehden nimi: BMC GENOMICS
Lehden akronyymi: BMC GENOMICS
Vuosikerta: 11
Sivujen määrä: 11
ISSN: 1471-2164
DOI: https://doi.org/10.1186/1471-2164-11-156
Tiivistelmä
Conclusions: The INDEL genotyping enabled fast coarse-mapping of chromosomal regions containing QTL, thus providing an efficient means for characterization of genetic architecture in multiple crosses and large pedigrees. This enables not only the discovery of larger number of QTLs with relatively smaller phenotypic effect but also provides a cost-effective means for evaluation of the frequency of segregating QTLs in outbred populations which is important for further understanding how genetic variation underlying phenotypic traits is maintained in the wild.
Conclusions: The INDEL genotyping enabled fast coarse-mapping of chromosomal regions containing QTL, thus providing an efficient means for characterization of genetic architecture in multiple crosses and large pedigrees. This enables not only the discovery of larger number of QTLs with relatively smaller phenotypic effect but also provides a cost-effective means for evaluation of the frequency of segregating QTLs in outbred populations which is important for further understanding how genetic variation underlying phenotypic traits is maintained in the wild.
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