Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012 - UTU Research Portal

A1 Refereed original research article in a scientific journal

Impact of Influenza B Lineage-Level Mismatch Between Trivalent Seasonal Influenza Vaccines and Circulating Viruses, 1999-2012

Authors: Terho Heikkinen, Niina Ikonen, Thedi Ziegler

Publisher: OXFORD UNIV PRESS INC

Publication year: 2014

Journal: Clinical Infectious Diseases

Journal name in source: CLINICAL INFECTIOUS DISEASES

Journal acronym: CLIN INFECT DIS

Volume: 59

Issue: 11

First page : 1519

Last page: 1524

Number of pages: 6

ISSN: 1058-4838

DOI: https://doi.org/10.1093/cid/ciu664(external)

Abstract

Conclusions. The population-level impact of lineage-level mismatch between the vaccine and circulating strains of influenza B viruses is substantial, especially among children and adolescents. The results provide strong support for the inclusion of both influenza B lineages in seasonal influenza vaccines.