A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Ring-Ring Tautomerism of the Products of the Reaction of 4-Hydroxytetrahydropyrimidine-2(1H)-Thiones with Functionally Substituted Amines and Hydrazines
Tekijät: V. V. Alekseyev, S. I. Yakimovich, I. V. Zerova, M. B. Egorova, J. Sinkkonen
Kustantaja: SPRINGER
Julkaisuvuosi: 2014
Journal: Chemistry of Heterocyclic Compounds
Tietokannassa oleva lehden nimi: CHEMISTRY OF HETEROCYCLIC COMPOUNDS
Lehden akronyymi: CHEM HETEROCYCL COM+
Vuosikerta: 49
Numero: 10
Aloitussivu: 1490
Lopetussivu: 1499
Sivujen määrä: 10
ISSN: 0009-3122
DOI: https://doi.org/10.1007/s10593-014-1400-z
A study was carried out on the reaction of 4-hydroxy-1-phenyltetrahydropyrimidine-2(1H)-thione and its 6-methyl analog with a series of functionally substituted hydrazines and amines. Substitution of the hydroxyl group leads to 4-substituted tetrahydropyrimidine-2(1H)-thiones. Partial recyclization is observed in solutions of the reaction products with thioaroylhydrazines and a ring-ring tautomeric equilibrium between tetrahydropyrimidine-2(1H)-thiones and 2,3-dihydro-1,3,4-thiadiazoles is established.
