Phasic non-micturition contractions in the bladder of the anaesthetized and awake rat

: Streng T, Hedlund P, Talo A, Andersson KE, Gillespie JI

Publisher: BLACKWELL PUBLISHING

: 2006

BJU International

BJU INTERNATIONAL

: BJU INT

: 97

: 5

: 1094

: 1101

: 8

: 1464-4096

DOI: https://doi.org/10.1111/j.1464-410X.2006.06137.x

The present results show the presence of NMCs in the rat bladder, identify volume-dependent changes in the pattern of this activity during the micturition cycle, and show that NMCs are accompanied by electrical changes in the detrusor. The physiological significance of NMCs is not known but it might be linked to the generation of afferent discharge from mechanoreceptors in the wall, so contributing to sensations related to bladder volume.