A1 Refereed original research article in a scientific journal
Transmitters contributing to the voiding contraction in female rats
Authors: Streng T, Talo A, Andersson KE
Publisher: BLACKWELL PUBLISHING LTD
Publication year: 2004
Journal: BJU International
Journal name in source: BJU INTERNATIONAL
Journal acronym: BJU INT
Volume: 94
Issue: 6
First page : 910
Last page: 914
Number of pages: 5
ISSN: 1464-4096
DOI: https://doi.org/10.1111/j.1464-410X.2004.05058.x
Abstract
CONCLUSIONS ATP contributes mainly to the initial and acetylcholine to the later phases of the voiding cycle in the rat. Neither agent abolished the IHPFOs; even after blocking the receptors for one transmitter and in the presence of IPHFOs, the bladder can still empty. However, if both receptors are blocked, overflow incontinence develops, suggesting that even if further transmitters are taking part in the voiding contraction, their physiological significance is questionable.
CONCLUSIONS ATP contributes mainly to the initial and acetylcholine to the later phases of the voiding cycle in the rat. Neither agent abolished the IHPFOs; even after blocking the receptors for one transmitter and in the presence of IPHFOs, the bladder can still empty. However, if both receptors are blocked, overflow incontinence develops, suggesting that even if further transmitters are taking part in the voiding contraction, their physiological significance is questionable.
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