Analyses of Gingival Adhesion Molecules in Periodontitis: Theoretical In Silico, Comparative In Vivo, and Explanatory In Vitro Models



: Gursoy UK, Zeidan-Chulia F, Yilmaz D, Ouml;zdemir V, Maki-Petays J, de Oliveira BHN, Firatli Y, Guncu GN, Caglayan F, Kononen E

Publisher: AMER ACAD PERIODONTOLOGY

: 2016

: Journal of Periodontology

: JOURNAL OF PERIODONTOLOGY

: J PERIODONTOL

: 87

: 2

: 193

: 202

: 10

: 0022-3492

DOI: https://doi.org/10.1902/jop.2015.150361


Conclusions: Gene expression of gingival adhesion molecules in periodontitis is regulated by leukocyte transmigration, whereas the neutrophilic antimicrobial peptide HNP-1 is noted as a putative regulator of epithelial adhesion molecules. These observations contribute to the key mechanisms by which future biomarkers might be developed for periodontitis.




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