Adhesion of Respiratory-Infection-Associated Microorganisms on Degradable Thermoplastic Composites

: Tirri T, Soderling E, Malin M, Peltola M, Seppala JV, Narhi TO

Publisher: HINDAWI LTD

: 2009

: International Journal of Biomaterials

: INTERNATIONAL JOURNAL OF BIOMATERIALS

: INT J BIOMATER

: ARTN 765813

: 6

: 1687-8787

DOI: https://doi.org/10.1155/2009/765813

The purpose of this study was to evaluate bacterial adhesion and early colonization on a composite consisting of bioactive glass (BAG) particles and copolymer of e-caprolactone/D, L-lactide. Materials were incubated with suspensions of both type strains and clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa for 30 minutes (adhesion) and 4 hours (colonization). Clear differences exist in the microorganisms' ability to adhere on the experimental materials. However, the presence of BAG particles does not inhibit bacterial adhesion, but early colonization of the materials with P. aeruginosa was inhibited by the addition of 90-315 mu m BAG particles. Copyright (C) 2009 Teemu Tirri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.