This chapter introduces theories of spatial economic development. There
is an extensive amount of international research evidence that the main
driving areas within nations are relatively large sized cities and their
regions. The growth often concentrates on a limited number of key
regions and cities of the world—mostly those are global cities of the
world. Their number on the other hand is dependent on the population and
geographical size of the nation. The relationship is not, however,
linear or simple question of size. The location advantaged specific for
each location have a significant impact and role on how it fits to the
needs of varying markets. Industrial history and the advantage of the
initiator are clearly visible in several key-hotspots in the technology
industries producing innovations.