A1 Refereed original research article in a scientific journal
Preanalytical conditions that affect coagulation testing, including hormonal status and therapy
Authors: Blombäck M, Konkle BA, Manco-Johnson MJ, Bremme K, Hellgren M, Kaaja R, Kaaja R
Publication year: 2007
Journal: Journal of Thrombosis and Haemostasis
Journal name in source: Journal of thrombosis and haemostasis : JTH
Journal acronym: J Thromb Haemost
Volume: 5
Issue: 4
First page : 855
Last page: 8
Number of pages: 4
ISSN: 1538-7836
DOI: https://doi.org/10.1111/j.1538-7836.2007.02401.x
Abstract
Preanalytical conditions, be they due to the individual's physiologic state or to exogenous factors, can affect coagulation factors, in either a transient or a persistent manner, and need to be considered in laboratory testing. These conditions include physical and mental stress, diurnal variation, hormone levels and posture at the time of blood drawing. While testing of these factors has not been exhaustive and some results are conflicting, guidelines for testing conditions can be given.
Preanalytical conditions, be they due to the individual's physiologic state or to exogenous factors, can affect coagulation factors, in either a transient or a persistent manner, and need to be considered in laboratory testing. These conditions include physical and mental stress, diurnal variation, hormone levels and posture at the time of blood drawing. While testing of these factors has not been exhaustive and some results are conflicting, guidelines for testing conditions can be given.