A1 Refereed original research article in a scientific journal
Oral health care patterns and the history of miscarriage
Authors: Heimonen A, Janket SJ, Meurman JH, Furuholm J, Ackerson LK, Kaaja R
Publication year: 2008
Journal: Oral Diseases
Journal name in source: Oral diseases
Journal acronym: Oral Dis
Volume: 14
Issue: 8
First page : 734
Last page: 40
Number of pages: 7
ISSN: 1354-523X
eISSN: 1601-0825
DOI: https://doi.org/10.1111/j.1601-0825.2008.01460.x
Abstract
Oral infections can trigger the production of pro-inflammatory mediators that may be risk factors for miscarriage. We investigated whether oral health care patterns that may promote or alleviate oral inflammation were associated with the history of miscarriage in 328 all-Caucasian women.\nOf 328 women in this cross-sectional cohort, 74 had history of miscarriage (HMC). Medical, dental and sociodemographic data were collected through clinical examinations, medical record searches and structured questionnaires.\nThe multivariate regression analyses indicated that urgency-based dental treatment demonstrated a significant association [odds ratio (OR) = 2.54; 95% confidence interval (CI): 1.21-5.37; P = 0.01] and preventive dental treatment demonstrated a marginally significant inverse association (OR = 0.53; CI: 0.26-1.06; P = 0.07) with HMC. Self-rated poor oral health had a non-significant positive association with HMC (OR 1.60; CI: 0.88-2.90).\nOur results provide sufficient evidence for hypothesis generation to test whether other precise measures of oral inflammation are associated with adverse birth outcomes.\nOBJECTIVE\nMATERIALS AND METHODS\nRESULTS\nCONCLUSION
Oral infections can trigger the production of pro-inflammatory mediators that may be risk factors for miscarriage. We investigated whether oral health care patterns that may promote or alleviate oral inflammation were associated with the history of miscarriage in 328 all-Caucasian women.\nOf 328 women in this cross-sectional cohort, 74 had history of miscarriage (HMC). Medical, dental and sociodemographic data were collected through clinical examinations, medical record searches and structured questionnaires.\nThe multivariate regression analyses indicated that urgency-based dental treatment demonstrated a significant association [odds ratio (OR) = 2.54; 95% confidence interval (CI): 1.21-5.37; P = 0.01] and preventive dental treatment demonstrated a marginally significant inverse association (OR = 0.53; CI: 0.26-1.06; P = 0.07) with HMC. Self-rated poor oral health had a non-significant positive association with HMC (OR 1.60; CI: 0.88-2.90).\nOur results provide sufficient evidence for hypothesis generation to test whether other precise measures of oral inflammation are associated with adverse birth outcomes.\nOBJECTIVE\nMATERIALS AND METHODS\nRESULTS\nCONCLUSION
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