A1 Refereed original research article in a scientific journal

Congenital heart block: successful prophylactic treatment with intravenous gamma globulin and corticosteroid therapy




AuthorsKaaja R, Julkunen H, Ammälä P, Teppo AM, Kurki P

Publication year1991

JournalAmerican Journal of Obstetrics and Gynecology

Journal name in sourceAmerican journal of obstetrics and gynecology

Journal acronymAm J Obstet Gynecol

Volume165

Issue5 Pt 1

First page 1333

Last page4

Number of pages2

ISSN0002-9378


Abstract
In mothers with anti-Ro-positive antibodies whose previous pregnancies have ended in deliveries of infants with congenital heart block, prophylactic therapeutic strategies are used to try to diminish the production and passage into fetal circulation of autoantibodies. Intravenous gamma globulin was given at 14 and 18 weeks' gestation and prednisone was given from 14 weeks' gestation to a woman with Sjögren's syndrome. The pregnancy ended with delivery of an infant without congenital heart block.



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