A1 Refereed original research article in a scientific journal
Congenital heart block: successful prophylactic treatment with intravenous gamma globulin and corticosteroid therapy
Authors: Kaaja R, Julkunen H, Ammälä P, Teppo AM, Kurki P
Publication year: 1991
Journal: American Journal of Obstetrics and Gynecology
Journal name in source: American journal of obstetrics and gynecology
Journal acronym: Am J Obstet Gynecol
Volume: 165
Issue: 5 Pt 1
First page : 1333
Last page: 4
Number of pages: 2
ISSN: 0002-9378
Abstract
In mothers with anti-Ro-positive antibodies whose previous pregnancies have ended in deliveries of infants with congenital heart block, prophylactic therapeutic strategies are used to try to diminish the production and passage into fetal circulation of autoantibodies. Intravenous gamma globulin was given at 14 and 18 weeks' gestation and prednisone was given from 14 weeks' gestation to a woman with Sjögren's syndrome. The pregnancy ended with delivery of an infant without congenital heart block.
In mothers with anti-Ro-positive antibodies whose previous pregnancies have ended in deliveries of infants with congenital heart block, prophylactic therapeutic strategies are used to try to diminish the production and passage into fetal circulation of autoantibodies. Intravenous gamma globulin was given at 14 and 18 weeks' gestation and prednisone was given from 14 weeks' gestation to a woman with Sjögren's syndrome. The pregnancy ended with delivery of an infant without congenital heart block.