A1 Refereed original research article in a scientific journal

Voiding effects mediated by alpha(2)-adrenoceptors in the anaesthetized male rat



Authors: Streng T, Santti R, Andersson KE

Publisher: WILEY-BLACKWELL

Publication year: 2010

Journal: BJU International

Journal name in source: BJU INTERNATIONAL

Journal acronym: BJU INT

Number in series: 10

Volume: 106

Issue: 10

First page : 1546

Last page: 1549

Number of pages: 4

ISSN: 1464-4096

DOI: https://doi.org/10.1111/j.1464-410X.2010.09228.x


Abstract
Stimulation and blockade of alpha(2)-ARs have a significant effect on lower urinary tract function. If the data from this rat model are also valid in humans, a study of the effects of atipamezole on urethral sphincter activity and urethral pressures in humans would be of interest, and might show therapeutic potential of the drug.


Keywords:
cystometry, LUT function, male rat, urodynamics



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